Hepatocellular carcinoma.all spleen and partial liver resection.later,secondary systemic cancer metastasis.any targeted therapy or immunotherapy?

Yes, for both: Hepatocellular Carcinoma is commonly treated with Sorafenib which is a type of targeted therapy. This is a good choice of treatment in case you have not yet received this drug. Immunotherapy using PD-1 inhibitors has also shown some modest evidence of benefit although it is not yet FDA approved for this indication. Ask your oncologist to guide your treatment further.

Dr Zimon and another doctor agreed