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A 27-year-old female asked:

Can i safely take 150mg bupropion xl, 100mg sertraline and 10mg methylphenidate at the same time? what is my risk of seizure (no prior history)?

1 doctor answer6 doctors weighed in
Dr. Bac Nguyen
Family Medicine 25 years experience
+++interactions..: There are interactions among these three medications, and taken all 3 at the same time increases this chance and thus caution is advised. I would suggest discussing treatment option or regimen with your prescribing physician. As with all drugs or medications, take "smallest effective dose for the shortest duration possible" Good luck
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Last updated Oct 21, 2017

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