Took levaquin last year, had strange intense dreams while on it. ever since, periodic episodes of strange dreams..can this med alter brain chemistry?

Yes: Post-marketing describes strange or vivid dreams in <1% of the patients taking the medication. No report on how long the symptoms can last.

Neurotoxicity is: when something alters the normal activity of the nervous system in such a way as to cause damage to nervous tissue. Although rare, it may occur with many antibiotics including Levaquin (Levofloxacin). Strange dreams, mood and other mental changes may occur. They should subside when the medication is withdrawn but may require specific treatment. Best regards.