Can i take melatonin 5 mg oral and oxycodone 10 mg oral ?

That' ll work & Safe: Usually I tell my patients to take melatonin in a sub-lingual preparation (under the tongue) 10 to 15 minutes before you are to turn out the lights for sleep, as the swallowed type is much less effective. It becomes inactivated in the stomach by the high acid content. As for taking it with oxycodone. This combo should be fine beware they both can cause drowsiness and you may have some impairment