A member asked:

Is it unsafe to take ibuprofen, aleve and hydrocodone together for severe tooth pain? what are the side effects?

4 doctors weighed in across 4 answers

Yes. Do not take!: Ibuprofen and aleve (naproxen) are both NSAIDs and taking them together can dramatically increase the risk for bleeding, ulcers, kidney failure, and even heart attacks. Do not take them together. Ibuprofen is also known by the brand names Advil and Motrin. Naproxen is known by brand names Aleve and Naprosyn. Other NSAIDs are indomethacin, Celebrex, Mobic, Toradol, Voltaren, and others. Do Not Mix!

Answered 12/4/2016

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Dr. Keith Hollander answered

Specializes in Dentistry

Need more data: Ibuprofen and Aleve are similar drugs and should not be taken together (could be too much of the same kind of thing). Does the Hydrocodone have any Acetaminophen in it? You can take that with the Ibuprofen. You might want to try just taking Ibuprofen and Tylenol (acetaminophen) together without the narcotic. Research shows its as good or better for pain than the narcotic. Talk to your dentis

Answered 8/27/2018

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Dr. Louis Gallia answered

Specializes in Surgery - Oral & Maxillofacial

Overdose NSAIDS: You can cause kidney damage by too much ibuprofen and aleve. Don't take toether. Hydrocodone and tylenol or NSAIDs are safe. Only reasonable course is to see DDS ASAP.

Answered 12/10/2016

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Severe pain: Most common cause of tooth pain is advanced infection. Pain killers don't treat infections, only block sensory nerve impulses as infection worsens. You're overdosing on pain killers. Please see Dentist ASAP. Pill popping counter productive.

Answered 6/13/2018

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