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A 40-year-old male asked:

What would cause extremely low hypocellular bone marrow - 15% normal, 65% really hypocellular and 15% mild-moderately low; i am 40 yr old male with 20lbs weight loss, spinal pain, sob, headaches, low ferritin and really high b12, folate; normal spep.

2 doctor answers2 doctors weighed in
Dr. Sewa Legha
Medical Oncology 50 years experience
Not a fixed number!: Bone marrow cellularity tends to be very variable in different people and there is room for sampling error as the marrow is not a uniform sheet of cell; instead it is normally quite patchy. if your blood counts(CBC) are normal, then the cause of your weight loss is not related to your Bone marrow cellularity. Look for other causes...elsewhere in the body.
Dr. Al Hegab
Dr. Al Hegabanswered
Allergy and Immunology 40 years experience
One marrow failure : can be due to several causes as radiation, certain drugs, tumours, and others. You need to be under the care of a hematologist, whom you may have already seen, kindly keep the follow up, wish you all the best, at this limited platform we can't really offer much in your case, good luck

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Last updated Jan 5, 2019

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