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A 29-year-old male asked:

anemic with 1.2% retic count, 0.62 red cell production index. whites/platelets normal. bone marrow problem? i'm anemic, male, hemoglobin 11.5, hct 34.5, red cells 3.9. iron, ferritin, b12, folate all good, no gi bleed (upper endoscopy and fecal occult n

3 doctor answers4 doctors weighed in
Dr. Mary Engrav
Dr. Mary Engrav answered
Emergency Medicine 31 years experience
No, : No, this does not necessarily indicate that your bone marrow is not producing enough red blood cells. You have had a complete workup it sounds like. You are slightly anemic. You have a normal reticulocyte count. To put your mind at rest, you can discuss your findings with a hematologist, who may have recommendations, but your numbers are not concerning.
Dr. Stephen Christensen
Family Medicine 35 years experience
As : As you probably know, a reticulocyte index below 2% indicates red cell hypoproliferation, or an inadequate marrow response to a low red blood cell count. (your normal iron studies and red blood cell indices indicate your anemia is not caused by iron deficiency.) hypoproliferative bone marrow can be seen in several situations, including those that readily respond to treatment (medications, infections, etc.) and those that are refractory to treatment (kidney failure, myelodysplasia, etc.). Some causes of red cell hypoproliferation are transient. A hematology workup would be useful if your anemia is persistent. I hope things go well for you!
Dr. Liawaty Ho
Hematology and Oncology 23 years experience
Hypoproliferative: What is the mcv? There is a possibility that you may have a hypoproliferative marrow with the reticulocyte index of 0.62. ( my calculator showed me it is 0.44). There are many different things can cause hypoproliferative anemia. See a hematologist for further work-up.

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Last updated Sep 2, 2020

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