A member asked:

What is the definition or description of: progeria?

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A rare condition : Progeria is a rare hereditary condition affecting the blood vessels, skin and musculoskeletal system that creates the impression of accelerated aging. Some aging processes are truly accelerated such as atherosclerosis of the coronary and carotid arteries, resulting early death. Most of the other illnesses of aging such as cancer, cataracts, and dementia do not occur but deposition of a substance associated with aging, liposuction, in vital organs leads to impairment of the liver, heart, adrenal glands, brain and skeletal system. Another protein, progeria, leads to defective DNA expression and repair. This protein also enhances the development of atherosclerosis. Children with Progeria have brittle bones, pathological fractures, feeding problems, dental abnormalities, hearing loss, growth failure, hairless, and clotting problems. Characteristic facial features are described.

Answered 9/7/2020

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Dr. Heidi Fowler answered

Specializes in Psychiatry

Progeria: Progeria (Hutchinson–Gilford progeria syndrome (HGPS))is an autosomal dominant genetic disorder which is usually due to new mututions. It causes characteristics of early aging. Cardiovascular problems usually result in death.

Answered 9/7/2020

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