A member asked:

How conclusive is a negative 4th gen hiv duo test at 7 weeks for all practical purposes?

2 doctors weighed in across 2 answers
Dr. Hunter Handsfield answered

Specializes in Infectious Disease

100%: Totally reliable any time 4 weeks or more after the last possible exposure.

Answered 4/28/2020

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Dr. David Lipkin answered

Specializes in Internal Medicine

It's conclusive.: The p24 antigen is a viral core protein that appears in the blood as the viral RNA level rises following HIV infection. The test turns (+) 5-7 days after viral RNA appears in the blood. It is 89-100% as sensitive as viral RNA.This assay detects a level of antigen that approximately corresponds to an HIV RNA level of 30,000 to 50,000 copies/mL .

Answered 1/29/2020

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