Depends on severity: & resulting severity of: hypoxemia, resulting pulmonary hypertension & severity of underlying coronary artery disease (in 1/2 of US citizens by age 7, per >8 decades US autopsy studies; yet asymptomatic for decades; arteries enlarge: http://goo.gl/aRhOU2. Narrowings, most clinically silent, result from sudden plaque ruptures & clots). Thus there is no reliable answer-too many individual variables.
Answered 8/21/2016
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