A member asked:

Is it common to have sarcoidosis diagnosed from a skin biopsy? lung xray was negative. what does this mean?

7 doctors weighed in across 3 answers

Yes: Get a couple of pathologists to sign off on it, but the appearance of sarcoid is distinctive on skin biopsy. It's a perennial fooler & can pop up at the most surprising times. The most important thing for a patient to know about sarcoid is that often the best treatment is little-or-nothing. Good luck & stay proactive.

Answered 12/9/2013

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Sarcoid: Sarcoid can affect many organ systems. If there is a tissue diagnosis based on a skin biopsy it is most likely correct. Although pulmonary signs are common, there are many people with biopsy proven sarcoid who do not have lung or chest problems or findings.

Answered 4/14/2013

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Sarcoidosis: Sarcoidosis can be suspected from a skin biopsy. Sarcoidosis primarily affects the lungs (90%), skin (25%) and eyes, although most other organs can be affected, including the nervous system and joints. There are other conditions that can look like sarcoidosis on biopsy include certain infections, foreign body reactions, drug reactions and other inflammatory conditions. These need to be excluded.

Answered 5/15/2014

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