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A 28-year-old female asked:

Am 28y and my first baby is down , its bciz random mutation what the chance to have another one with down ?!

1 doctor answer1 doctor weighed in
Dr. James Ferguson
Pediatrics 47 years experience
About 1% added : The basic of a trisomy 21 ds varies with age, being 1/800 at 30-34, 1/270 at 35-40.A previous ds birth adds 1% if it was a traditional trisomy 21 ds . A discussion with a geneticist affiliated with a med school or kids hospital could provide with all your risk factors in detail.
Last updated Apr 9, 2013

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