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A 40-year-old female asked:

simple partial seizure, 26 mos since last episode, on keppra (levetiracetam) 250mg once a day for 26 months. what's recommended weaning schedule?

1 doctor answer1 doctor weighed in
Dr. Bennett Machanic
Neurology 52 years experience
Take your time: It may or may not be safe to stop your medication at this point. I usually wait at least 3 yrs, and if totally seizure free over this time, I check an EEG, and repeat neurological exam. If all is well, would wean over about 3-4 months. But, you are taking exceptionally low dose of Keppra, (levetiracetam) which is likely sub therapeutic. Work closely with your neurologist.

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Last updated Dec 11, 2019

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