A member asked:

Cousin takes thorazine (chlorpromazine) for schizophrenia.it works well. he developed tardive dyskinesia but its very subtle so dr doesnt want to take him off. normal?

11 doctors weighed in across 3 answers
Dr. Pacita David answered

Specializes in Psychiatry

Certainly possible: Tardive dyskinesia is a condition consisting of involuntary movements, more commonly of the tongue and lips. It can also involve the face, trunk and extremities. TD is a potential side effect of all antipsychotics, but more likely in first generation ones such as Thorazine, (chlorpromazine) vs. second generation. Decision to continue depends on patient response to treatment and degree of debilitation. Best.

Answered 3/15/2017

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Dr. Krishna Kumar answered

Specializes in Psychiatry

Tardive Dyskinesia: The symptoms of Tardive Dyskinesia are- involuntary • Facial grimacing • Swinging of the jaw • Repetitive chewing • Tongue thrusting and twisting • Puckering & smacking of the lips • Rapid eye blinking & eyebrow raising • Grunts and humming Go with your cousin to see Psychiatrist, inform about your observations and concern; and discuss management of Thorazine (chlorpromazine) and Day Treatment Center for recovery.

Answered 11/28/2017

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Dr. Patricia Foster answered

Specializes in Psychiatry

TD: Tardive dyskinesia is related to total exposure to Thorazine (chlorpromazine) or similar meds; ie, the higher the dose and longer the time taking the med, the greater the risk of TD worsening. Since it's been already observed, would recommend reassessing for a lower dose with prescribing doctor. Weigh risks of TD vs benefits of present dose. See: http://www.nami.org/Learn-More/Mental-Health-Conditions/Related-Conditions/Tardive-Dyskinesia I hope this helps. Best wishes.

Answered 4/24/2016

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