A member asked:

Just started on synthroid (thyroxine) (finally!!!) how long before symptoms improve (cold intolerance, brittle nails, hair falling out, constipation? what side effects should i watch for or expect? how long before dose increase?

7 doctors weighed in across 2 answers
Dr. Richard Zimon answered

Specializes in Internal Medicine

I usually advise: my thyroid patients that it may be SEVERAl WEEKS for them to notice a "difference" and THAT is when I re-check the tests at 2 weeks to begin with! The "cold intolerance " is usually the first to "respond" BE PATIENT!!! It may take several visits before your problem is "sorted out" Hope this helps! Dr Z

Answered 3/31/2016

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Dr. Charles Gordon answered

Specializes in Adolescent Medicine

Very quickly: Your doctor will monitor the dose of thyroid replacement hormone that you are taking by having you get blood tests for TSH (Thyroid Stimulating Hormone). If your pituitary gland feels there is not enough thyroxine in your blood it will secrete more TSH. You will then take more thyroid hormone until TSH drops to the normal range. And you'll feel much better!! Take it 1 ht before meals. Absorption a

Answered 3/27/2016

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