Imhave mild arthritis in right thumb have pain in hand and lowerback pain after sleep and knee pain and fatigue what are these symptom?

Joint pain: It is common to have joint pain upon awakening when people reach their 50-60, fatigue has so many things it can be associated with it would be hard to provide advice without a consult. So.. If these symptoms are becoming more pronounced you should be evaluated

Check up: I would probably start with a good medical check up, your symptoms may or may be related. There are some conditions that can cause joint pain and fatigue, such as an undiagnosed inflammatory arthritis; but again, it may be more than one condition as well.