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A 46-year-old female asked:

Can an antidepressant like zoloft (sertraline) cause some memory loss ? i've been taking it over a mo. (25mg) and notice im forgetful. can it become permanent?

2 doctor answers4 doctors weighed in
Dr. Elena Padrell
Psychiatry 40 years experience
Rare: It is very rare that such low dose of Sertraline could cause memory loss, on the other hand because of dose being low and almost negligent, Ok to get off and check if your cognitive sx's improve. If not, explore other reasons towards forgetfulness, perimenaupausal?, check hormone levels and other sx of depression.
Dr. Edward Kuhnley
Child Psychiatry 45 years experience
Memory loss rare but: possible with zoloft, (sertraline) steroids, metrogel. More common in conditions treated by zoloft: anxiety, depression, menopause. Timing of occurrence relevant to medications and conditions may suggest which if not all are contributing. Improve memory: stay mentally active, socialize regularly, get organized, sleep well, eat healthy, get physical. Consult prescriber if problematic. Best regards for relief.

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Last updated Jun 9, 2020

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