HealthTap Online Primary Care Doctors Accepting New Patients
Book a video visit
HealthTap
Telehealth
A member asked:

I took pseudophedrine & excedrine at 6 pm and used a nasal spray w/ phenylephrine hcl. it's now around 2:30 am. would it be okay to take nyquil?

A doctor has provided 1 answer

Be careful: Pseudoephedrine and phenylephrine are stimulants and Excedrin contains caffeine, all of which if taken together could cause nervousness jitteriness and possibly palpitations. Do NOT overmedicate. Nyquil can be sedating in certain individuals.

Answered 2/5/2016

1.7k views

Thank

Related Questions

A member asked:

Can you take either afrin nasal spray or sudafed nasal congestant with nyquil?

8 doctors weighed in across 3 answers

A member asked:

Can you take sinex nasal spray and sinex dayquil/nyquil liquicaps together?

A doctor has provided 1 answer

A member asked:

Can you take a nasal spray decongestant with NyQuil?

A doctor has provided 1 answer

A member asked:

Can I take Flonase nasal spray 24 Hour and then take NyQuil severe cold and flu 4 hours later?

A doctor has provided 1 answer

A member asked:

Mistook phenylephrine Hydrochloride 1% nasal spray for my saline nasal spray so I sprayed a lot. Used neti pot afterward to get out as much as i could?

A doctor has provided 1 answer

Sponsored Content
HealthTap Medical Group does not endorse products or services. Sponsored content revenues support our mission to make health information free and accessible to all.Learn more

People also searched for:

Okay to take a decongestant (400mg guaifenesin + 10mg phenylephrine hcl) while I am doing an allergy patch test? Nose is stuffy, congestion in lungs.
Can you take Mucinex Daytime (dextromethorphan, guaifenesin, & phenylephrine) with Azelastine nasal spray?
Can I take NyQuil if I took Alegra for allergies 6 hours ago? I also used fluticasone nasal spray
Can i take benzonatate 100 mg at 3pm, phenylephrine hcl 10 mg at 4 pm, and loratadine 10 mg at 5:30 pm?
Can I take afrin nasal spray(12 hours) with NyQuil together?

Telemedicine

Primary Care
Manage Your Conditions
Women's Health
Children's Health
Men's Health
Senior Health
Wellness, Prevention & Lifestyle
Sexual Health
Mental & Behavioral Health
Travel Medicine
Urgent Care
Ask your question
Didn't find what you're looking for?

90,000 U.S. doctors in 147 specialties are here to answer your questions or offer you advice, prescriptions, and more.

Ask your question

More of what we treat

Allergies
Antibiotics
Asthma
High Blood Pressure
Prescriptions
Type 2 Diabetes
Content on HealthTap (including answers) should not be used for medical advice, diagnosis, or treatment, and interactions on HealthTap do not create a doctor-patient relationship. Never disregard or delay professional medical advice in person because of anything on HealthTap. Call your doctor or 911 if you think you may have a medical emergency.
HealthTap
HIPAA logo
HIPAASecure
Soc 2 Type 2 logo
SOC 2 Type 2Certified
JCAHO Accredited
JCAHOAccredited
Member App

Download HealthTap

Video visit and message your doctor

Member App QR Code
Play Store Member LinkApp Store Member Link

Questions?

+1 (888) 828-0841support@healthtap.com
LinkedInTwitter
HomeTermsPrivacyCookiesDMCAHealth TopicsDoctors DirectoryDoctor Q&A by Specialty
Copyright 2026 HealthTap, Inc.