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Addison, IL
A 48-year-old female asked:

Fioricet 50/325/40 for migraines,knee surgery 40days ago,still norco (hydrocodone and acetaminophen) 1-10/325 before pt. can i take them together if need to, with 1-2 hrs.apart)?

2 doctor answers5 doctors weighed in
Dr. Paul Grin
Pain Management 38 years experience
Yes, you can : However, may increase side effects such as dizziness, drowsiness, and difficulty concentrating. Always take these medications on a schedule as directed by your doctor.
Created for people with ongoing healthcare needs but benefits everyone.
Dr. Bennett Machanic
Neurology 54 years experience
Sorry, this is more than a nasty combination, it is dangerous, and the frequency is actually life threatening. Both can depress the central nervous system, prompting potential apnea, especially while sleeping. These drugs are best separated by at least 6-8 hrs, and should NEVER be ingested together.
Created for people with ongoing healthcare needs but benefits everyone.
Last updated Apr 14, 2021

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