A 48-year-old female asked:
Fioricet 50/325/40 for migraines,knee surgery 40days ago,still norco (hydrocodone and acetaminophen) 1-10/325 before pt. can i take them together if need to, with 1-2 hrs.apart)?
2 doctor answers • 5 doctors weighed in
Dr. Paul Grinanswered
Pain Management 38 years experience
Yes, you can : However, may increase side effects such as dizziness, drowsiness, and difficulty concentrating. Always take these medications on a schedule as directed by your doctor.
1.8k viewsReviewed >2 years ago
Dr. Bennett Machanicanswered
Neurology 54 years experience
Sorry, this is more than a nasty combination, it is dangerous, and the frequency is actually life threatening. Both can depress the central nervous system, prompting potential apnea, especially while sleeping. These drugs are best separated by at least 6-8 hrs, and should NEVER be ingested together.
Reviewed Apr 14, 2021
Last updated Apr 14, 2021
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