A member asked:

What is correct/best timing for taking vyvanse(40mg) & venlafaxine hcr xl(75 mg)? (age 59, recently diagnosed add, clinical depression since 2007)

A doctor has provided 1 answer

Caution: Vyvanse (lisdexamfetamine) interacts with Venlafaxine to increase side effects of Vyanse, eg, jitteriness, anxiety. Taking both meds also increases risk for serotonin syndrome which is too much serotonin in the system causing confusion, increased heart rate etc. This may occur regardless of timing of dose. Review with prescribing doc for guidance. I hope this helps. Best wishes.

Answered 5/31/2017

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