A member asked:

Hello; have been on endep (amitriptyline) 50mg for four months now. what is the schedule for tapering off. thanks?

2 doctors weighed in across 2 answers
Dr. J Rodos answered

Need to know more: first you have to be symptom FREE! other-wise you will relapse. second, relates to number of previous episodes. this determines the length of treatment before a taper of dose is undertaken. In depression, for example, if there has been more than 4 episodes, long term therapy is advised.

Answered 11/27/2015

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Dr. Edward Kuhnley answered

Specializes in Child Psychiatry

Amitriptyline 50 mg: is a low dose but withdrawal symptoms may occur. Best to discuss discontinuation with prescriber. For gentle taper reduce dose in half for a week or 2. If no relapse of target symptoms nor appearance of uncomfortable withdrawal symptoms (nausea, headache, malaise, irritability, restlessness, and dream/sleep disturbance), then may stop. Take half last dose if withdrawal symptoms. Best regards.

Answered 11/27/2015

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