Need medical eval: Yes, Pristiq (desvenlafaxine) can cause weight gain but so can bulimia, depression, thyroid disorder, abnormal blood sugar etc. Get checked by your pcp to rule out medical factors for weight gain. Talk to prescribing doctor about weight gain on Pristiq (desvenlafaxine) and review alternate meds. Would add therapy to help you work on eating disorder, depression and chain smoking. I hope this helps and you feel better soon.
Answered 4/26/2016
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