A member asked:

I've noticed my ankles have become very swollen lately, and i've had a lot of leg pain. taking prednisone and pentasa (mesalamine). should i contact my doctor?

A doctor has provided 1 answer

Yes: Prednisone can definitely cause fluid retention which tends to build up in the lower extremities. I would recommend having this evaluated immediately by your physician due to the other less likely possibility of blood clots causing obstruction of the veins in your legs. If their are no clots -- compression stockings may help with the swelling along with medicine to reduce the fluid retention.

Answered 6/15/2018

2.5k views

Thank

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