A member asked:

Some of my aunts had hnpcc 1 died colon cancer@ 34. i have no cancer yet and am 43 am i or my kids still @ higher risk of colon cancer?

3 doctors weighed in across 2 answers

Yes: With hereditary nonpolyposis colorectal cancer or Lynch syndrome there is an autosomal dominant genetic condition associated with a high risk of colon cancer as well as other cancers including endometrial cancer ovary, stomach, small intestine, This is due to inherited mutations that impair DNA mismatch repair. Absence of malignancy now can result in cancers appearing later.

Answered 7/6/2015

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What is your status?: You have a right to have your germline status for the mutation checked. Ask your physician.

Answered 7/6/2015

2.6k views

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