A 33-year-old member asked:
For what reason colon part is usually prone to cancer in hnpcc (hereditary hereditary nonpolyposis colorectal cancer)?
1 doctor answer • 4 doctors weighed in
Dr. Gurmukh Singhanswered
Pathology 51 years experience
Genetic disorder: Hnpcc also called lynch syndrome results from at least four type of genetic defects involving genes needed for repair of damaged dna. See this site for more info.
http://ghr.nlm.nih.gov/condition/lynch-syndrome.
Created for people with ongoing healthcare needs but benefits everyone.
4.6k viewsReviewed >2 years ago
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A 49-year-old member asked:
Why is the colon prone to cancer in hnpcc (hereditary nonpolyposis colorectal cancer)?
1 doctor answer • 1 doctor weighed in
Dr. Myron Arlenanswered
Surgical Oncology 66 years experience
Genetic mutations: HNPCC or hereditary nonpolyposis colorectal cancer is an autosomal dominant genetic condition that has a high risk of colon cancer The disease first described by Lynch and is associated with other cancers including endometrial ovary and stomach. The increased risk is due to inherited mutations that impair DNA mismatch repair. .Individuals with HNPCC have an 80% lifetime risk for colon ca.
Created for people with ongoing healthcare needs but benefits everyone.
3.3k viewsAnswered >2 years ago
Last updated Dec 30, 2013
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