Hemerrhoids during first trimester what's the best thing to use cream or suppositories?

Both work: Both creams and suppositories work equally well. The same ingredients can be in either form. It is a matter of personal preference which to choose. Do try to keep your stools soft with fiber and fluids since both diarrhea and constipation can aggravate hemorrhoids as can any lifting or straining. Hope this helps. Best wishes to you and the baby.