How can cigarette smoke go from outside the body to inside the blood stream?

Several Ways: Nicotine moves right into the small blood vessels that line the tissues listed . Skin lungs mucous membranes inhalation nicotine moves right into the small blood vessels that line the tissues listed above. From there, nicotine travels through your bloodstream to the brain, and then is delivered to the rest of your body. From there, nicotine travels through your bloodstream to the brain, an.