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A 27-year-old male asked:

Can clozaril (clozapine) cause akathisia, restlessness?

2 doctor answers5 doctors weighed in
Dr. Bennett Machanic
Neurology 53 years experience
Can occur: These side effects would occur while taking Clozaril, but if you have stopped and instead suffer restless leg syndrome, would suggest checking iron metabolism, with ferritin level, and considering use of a dopamine agonist around the clock (suggest Neupro (rotigotine) patch). Talk to your doctor about these thoughts.
Created for people with ongoing healthcare needs but benefits everyone.
Dr. Heidi Fowler
Psychiatry 26 years experience
Clozapine: Akathisia is considered to occur less with Clozapine that with many other antipsychotic medications. It has occurred with Clozapine withdrawal.
Created for people with ongoing healthcare needs but benefits everyone.

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Last updated Jan 9, 2021


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