Hi! do you know if i can take afrin (oxymetazoline) and flonase together?

Yes: Afrin typically should not be used for more than 5 or so consecutive days. Tolerance develops at that point and congestion can worsen. There are studies that suggest nasal steroid blocks development of tolerance, so some patients can actually tolerate Afrin longer. Ask your physician about this before extending use of Afrin and always consult physician before using either of these. Good luck!