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A member asked:

What is the significance of a low igm level in smoldering multiple myeloma?

A doctor has provided 1 answer
Dr. Tarik Hadid answered

Specializes in Internal Medicine - Hematology & Oncology

Part of the disease: Whenever you have smoldering myeloma of certain type, say IgG for example, the other antibody types like IgM and IgA are often decreased. It is just part of the disease process to see a paradoxical lower of other antibody types that are not involved in smoldering myeloma.

Dr Rhoads agreed

Answered 12/13/2015

2.9k views

Thank

Related Questions

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Resent blood work states IgM 875, an appearant polyclonal glammopathy IgM, kappa and Lambda light chains appear increased. Possible Multiple myeloma?

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A member asked:

I've had an elevated IgM for 1 year along with systemic symptoms. No monoclonal antibody, free light chains or Bence jones protein in urine so myeloma was eliminated and my infection screen and FBC is normal. What other diseases could cause high IgM?

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A member asked:

Does a low C4 level (10) always indicate a problem (such as myeloma, MGUS, auto immune)? Can it be just an insignificant test finding?

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Is ca level 9.5 after 6 month after tt without any ca supplement is normal or high? If high could it indicate to myeloma my goblin is 4.4 and ESR 12

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A member asked:

Gamma globulin level in test is 22.6%, results page they gave says this is higher than normal, normal range is listed as 11.1-18.8%. Concerned Myeloma?

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People also searched for:

If bone marrow aspirate results are reported as 10% plasma cells, does that mean smouldering myeloma? Is the core biopsy plasma cell % likely to be higher? I have an m-spike of 11.4 g/l IGA LAMBDA, low IGG and IGM. Am I in for scans next?
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What is the difference in testing an IgG and IgM bands for Lyme versus multiple myeloma?
How can I lower my IgM? Food? Exercise? Weight loss? I dont want multiple myeloma Gail?
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