Problematic: It is simplistic to say "dangerous," although that particular combination sounds problematic. The degree of risk would be dose-dependent. The interaction would likely include synergistic sedation, requiring clinical warning, and additional synergistic side effects, such as weight gain. But the combination raises questions about appropriateness: possibly a poor choice in an augmentation strategy.
Answered 6/21/2016
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Trazodone/Elavil: At high doses, can be overly sedating. Lower doses of 25-50mg. each should be ok. Keep in mind that addition of pain medications adds to the sedation.
Answered 4/7/2015
3k views
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