Myself 48 years ,my son 20yrs , daughter 11years are having renal glycosuria since birth , myself had taken no treatment since 1984 ,any treatment now?

No Rx needed, but I: recommend period screening for diabetes with HgbA1c or 2H PP blood glucose, to ensure that the ongoing glycosuria is not a reflection of diabetes, which would present the same way. Renal glycosuria is influenced by blood sugar levels, so focus on a diet with foods with a low glycemic index instead of simple sugars like pop and juice and stay well hydrated to minimize risk of kidney stones.