I tried to quit effexor (venlafaxine) xr but the symptoms came back. psch put me on zoloft 200m mg. how much time will it take to work?

Variable: This is a good question. As soon as a person takes a dose of Zoloft (sertraline) (or any SRI) their levels of serotonin in their brain begin to change. Some individuals likely benefit from that alone However...the secondary therapeutic actions relate to changes on the surface of the nerve cell which requires more complex mechanisms i.e protein synthesis...and this can take 2-4 weeks. So time is needed.

Not an easy question: There are numerous issues here. The degree of your condition, is a definite consideration. IN addition, your body's ability to get to the proper blood level is also a consideration. Some people metabolize drugs faster and some slower. We must also consider the proper dose for you which must be done over time. as you can see there is no simple answer. Good luck