A member asked:

Can benadryl (diphenhydramine) usage over a long term produce cause similar sexual side effects that ssris produce?

A doctor has provided 1 answer

Unlikely : Ssri side effects are very well established where as antihistamine use and sexual side effects are not that well established . I would be more concerned about long term use of antihistamine and the reasons for it . Are you using it for sleep , allergy ? Consult a psychiatrist as theses may be residual sx of depression and treatment may need to be optimized.

Answered 10/14/2016

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