How does heroin affect your liver health?

If pure, it doesn't: Opioids have little effect on the liver, but can cause gall bladder spasm, and even pancreatitis in some sensitive people. The major liver problems that result from heroin use are NOT from the heroin, but from contaminants in the drug, or sharing of needles and injection paraphernelia, or non-sterile injection techniques. Hepatitis B and C are the most common in the US, with cirrhosis&liver cancer