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A 35-year-old male asked:

My doctor has put me on lyrica (pregabalin) 600mg and tapentadol 100mg for my chronic pain. is this combo ok for long term use ?

1 doctor answer1 doctor weighed in
Dr. Karen Weisman
Addiction Medicine 30 years experience
May not be ok: with chronic use of both Lyrica (pregabalin) and Tapentadol, the possibility of side effects goes up. Some can be dangerous, e.g. a decrease in mental sharpness, increase risk for blood clots, etc. There is also an increase in propensity for weight gain.

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Last updated Aug 20, 2020

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