U.S. doctors online nowAsk doctors free
United Kingdom
A 35-year-old male asked:

My doctor has put me on lyrica (pregabalin) 600mg and tapentadol 100mg for my chronic pain. is this combo ok for long term use ?

1 doctor answer1 doctor weighed in
Dr. Karen Weisman
Addiction Medicine 30 years experience
May not be ok: with chronic use of both Lyrica (pregabalin) and Tapentadol, the possibility of side effects goes up. Some can be dangerous, e.g. a decrease in mental sharpness, increase risk for blood clots, etc. There is also an increase in propensity for weight gain.

90,000 U.S. doctors in 147 specialties are here to answer your questions or offer you advice, prescriptions, and more. Get help now:

Ask doctors free
Educational text
Talk to a doctor
24/7 visits - just $39!
50% off with $15/month membership
Last updated Aug 20, 2020


Content on HealthTap (including answers) should not be used for medical advice, diagnosis, or treatment, and interactions on HealthTap do not create a doctor-patient relationship. Never disregard or delay professional medical advice in person because of anything on HealthTap. Call your doctor or 911 if you think you may have a medical emergency.