Lower lip swells overnight since last two weeks. what to do?

See Allergist: Intermittent swelling with unknown trigger could be a sign that you have idiopathic angioedema (CIA). Common triggers include heat, cold, and viral infections. CIA is more common in females, average age of onset between 30-50yrs. Medications like ACE-inhibitors can also cause random swelling. Trial of daily antihistamines like Zyrtec (cetirizine) can be beneficial, screening C4 level can help reveal cause.