Been seen by multiple doctors,i have an enlarged spleen(8cm below lcm)pancytopenia high ldh and sed rate. what could cause this, my drs are stumped

Seek tertiary care: Your symptoms are non-specific. It could be an infection (epstein-barr virus) vs hematologic disorder vs autoimmune disorder. A visit to a tertiary, academic center may provide further insight into your underlying diagnosis

Splenomegaly: infectious, hematologic, storage diseases,vascular diseases, hepatic diseases,neoplastic diseases,connective tissue diseases, sarcoidosis, serum sickness etc. cover a very large number of possible disease states that need detailed consideration. You should seek evaluation from a hematologist who is willing to undertake a logical investigation. Splenomegaly puts you at risk at traumatic injury

Difficult to answer: A question like this would benefit from a HealthTap Prime consult, with labwork, biopsy results, and scan reports texted during the consultation. Knowing the full history and specific details would be extremely valuable.