~30-36 hours: If that is indeed the cause of your depression then it would take approximately 30-36 hours after your last dose of cipro (ciprofloxacin) to decrease to about 0.8% in your body. I would tell the person who prescribed you the cipro (ciprofloxacin) that you were stopping it. You were likely given cipro (ciprofloxacin) to stop some sort of infection, and only half treating infection can lead to antibiotic resistant infections.
Answered 2/3/2015
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