A member asked:

How can a medication like cymbalta (duloxetine) which raises norepinephrine help with anxiety as cymbalta (duloxetine) is approved for general anxiety at 60 mg.?

A doctor has provided 1 answer
Dr. John Gaffney answered

Specializes in Psychiatry

Norepinephrine: Norepinephrine is one of the neurotransmitters involved in attention, pain perception, heart rate, activation of the "fight or flight" system, and many others. Cymbalta (duloxetine) is a weak NE reuptake inhibitor ... So, in theory, it keeps more NE from being recycled out of the brain. By keeping more NE, the effects of anxiety on the body are decreased (theoretically). Hope that helps & good luck!

Answered 4/23/2016

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