A 20-year-old female asked:
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i've been on methylprednisolone for 2 weeks. 1st week was 16mg/day and 2nd was 12mg/day, now having trouble sleeping. any suggestion?

2 doctor answers
Dr. Gene Tekmyster
12 years experience Physical Medicine and Rehabilitation
It's common. : Sleeplessness and jitteriness is a common side effect is methylpredisone. Practicing good sleep hygiene will help. As the dose decreases and you continue to wean of the medication this will resolve. Be patient and it will get better.
Answered on Nov 27, 2017
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Dr. Myrtle Oates
38 years experience Obstetrics and Gynecology
Use only mild drugs: Hi Ruby, Insomnia is a common side effect with this drug . To help with sleeping you might try 'sleepy time tea' or camomile tea. I do not believe there would be any harm in small over the counter doses of Benadryl (diphenhydramine).
Answered on Apr 25, 2015
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1 thank

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A member asked:
Dr. George Ciechanowski
39 years experience Pulmonary Critical Care
Yes: the medrol can make you more hyper and therefore make it harder for you to sleep, so Xanax (alprazolam) may be helpful
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