A member asked:

Does the benefit of tysabri (natalizumab) outweigh the risk of pml ?

A doctor has provided 1 answer
Dr. Julie Abbott answered

Specializes in Preventive Medicine

Individualized: Tysabri/natalizumab is an immunosuppressant used in the treatment of relapsing forms of MS. PML (progressive multifocal leukoencephaolopathy),the result of JC virus infection, is a disastrous side effect.The decision to use this drug has to be very cautiously assessed by the MS patient & his doctor & administered through a restricted program. Risk/benefit analysis is complicated & challenging.

Answered 1/22/2015

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