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A 24-year-old male asked:

Does the benefit of tysabri (natalizumab) outweigh the risk of pml ?

1 doctor answer1 doctor weighed in
Dr. Julie Abbott
Preventive Medicine 45 years experience
Individualized: Tysabri/natalizumab is an immunosuppressant used in the treatment of relapsing forms of MS. PML (progressive multifocal leukoencephaolopathy),the result of JC virus infection, is a disastrous side effect.The decision to use this drug has to be very cautiously assessed by the MS patient & his doctor & administered through a restricted program. Risk/benefit analysis is complicated & challenging.

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Last updated Jan 22, 2015
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