Odd: Water pills ought to be taken in the morning, not night, so that you can sleep at night. Taking a water pill at night will disturb your sleep. Further, I am not sure what your additional risk factors for heart disease are, but Toprol (metoprolol) XL would not be my go to 2nd drug, rather an ACE inhibitor. THE ace inhibitor and HCTZ can be taken together in the morning.
Answered 2/11/2015
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