Biopsy is best: If lymphoma cells are circulating in the bloodstream, they might be able to be identified by flow cytometry (which is a test for lymphocyte surface markers). However, the most reliable method would be to perform a biopsy of any enlarged lymph node. Plus, if there is lymphoma, there are important aspects of a biopsy diagnosis that cannot be derived using a blood test.
Answered 4/1/2013
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