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A 72-year-old male asked:

I've heard of bile acid secuestrants as an alternative to statins for high cholesterol. what are the negatives to using them?

1 doctor answer3 doctors weighed in
Dr. Jerome Zacks
Cardiology 51 years experience
Partly helpful.: While bile acid sequestrants can help lower cholesterol, statins not only lower the LDL ("bad cholesterol"), but also have what are termed "pleiotropic effects" upon endothelial function, the stability of atherosclerotic plaques, decreasing oxidative stress and inflammation, and inhibiting the clotting response. Statins seem to have antitumor and other effects as well.

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Last updated Sep 2, 2019

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