A member asked:

Is there a medication comparable to abilify (aripiprazole) to treat bipolar disorder that doesn't cause weight gain?

14 doctors weighed in across 5 answers

Abilify (aripiprazole) options: Unfortunately, pretty much all of the treatments for bipolar disorder have some risk of weight gain, regardless of what the drug companies say. I have usually found Abilify to be one less prone to weight gain. But since it is not so for you, and you want to stick to meds in the same class, geodon, saphris, (asenapine) and Latuda might be reasonable options to consider. Please speak with your doctor about it.

Answered 10/3/2016

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Dr. William Holmes answered

Specializes in Child Psychiatry

Potentially Yes: Ability does not cause weight gain with the same frequency as some other meds. There are similar meds that may be less likely to contribute to weight gain, such as saphris (asenapine) or geodon. There are is also another class of meds, the anticonvulsants, which are used fir bipolar disorder and which may not cause a problem with weight. Not everyone will experience the same side effects with the same med.

Answered 5/7/2016

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Abilify (aripiprazole) and wt gain: Abilify is one of several second generation antipsychotic medications. Geodon (ziprasidone) in my experience often leads to wt loss. Other medications include medications also used to treat seizure problems, and for many may be quite effective, although also cause wt gain, for example depakote.Tegretol, which requires special expertise to give because of certain side effects, can be effective without wt gain.

Answered 5/7/2016

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Dr. Alan Ali answered

Specializes in Psychiatry

Abilify (aripiprazole): Abilify is low on scale of antipsychotics causing weight gain. If it does, a possible alternative would be geodon, (ziprasidone) but here you need to monitor your cardiac status.

Answered 9/28/2016

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Dr. Alan Ali answered

Specializes in Psychiatry

Bipolar/abilify: Also, topamax (topiramate) can be an option.

Answered 5/7/2016

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