A member asked:

Am taking naproxen for sciatica twice a day, can i take percocet for the pain in the evening as well?

9 doctors weighed in across 3 answers

Yes: Percocet is an opiate pain medication (oxycodone) and tylenol (acetaminophen). Naproxen is an nsaid. These are different medication classes and can be used together. However, i would caution against long term use of naproxen, as nsaids have many side effects including stomach ulcers, bleeding, blood pressure issues, and kidney failure.

Answered 11/11/2020

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Dr. Brian Le answered

Specializes in Pain Management

Naproxen & Percocet: Naproxen is an anti-inflammation medication. Percocet is a narcotic pain killer. They are prescribed together to treat many painful conditions. You can take them together, just be aware that both of them have side effects and Percocet has great addiction potential.

Answered 3/31/2016

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Dr. Qamar Khan answered

Specializes in Pain Management

Speak with doctor: Never change your dose of medication without consultation of your physician. You may need to discuss with you doctor what options you have regarding this issue.

Answered 7/20/2014

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