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A 63-year-old male asked:

I have been taking allopurinol for 1 week. i now have a gout attack. can i take colchicine as well? i

2 doctor answers4 doctors weighed in
Dr. Ronald Krauser
A Verified Doctoranswered
Rheumatology 54 years experience
Yes: You should never be started on Allopurinol alone as it commonly can precitpitate gout early in the treatment. Always take Colchicine 1 tab daily with it until your serum uric acid level is stable at 6 mg/dl or less. Hold Allopurinol during the acute attack and treat the attack either with Prednisone or nsaids. Colchicine is not my first choice for acute attacks.
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Dr. Thomas Namey
Rheumatology 50 years experience
Wrong order!: Taking Allopurinol during an attack will worsen and prolong it. My regimen is this: establish diagnosis. You can start an nsaid, inject the affected joint(s) with steroids, start colchicine, bid is adequate with the other meds. After three days start Allopurinol 100mg x 1wk, 200mg x 1wk, and then the full dose. The cochicine can be cut back to once daily.
Created for people with ongoing healthcare needs but benefits everyone.
Last updated Aug 28, 2020


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