A member asked:

Does metformin 500 cause missed periods?was put on it for pcos but had regular cycles before tht.was also diagnosed with hypothyroid but under control

3 doctors weighed in across 3 answers
Dr. Milroy Samuel answered

Specializes in Obstetrics and Gynecology

No: Assuming you have pcos you shouldn't have amenorrhea. Take a pregnancy test.

Answered 3/14/2013

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Generally no: Metformin is used to induce normal menses if you have pcos. Usually you need at least 1000-2000 mg/day in divided doses. Hypothyroidism can also affect periods, as can many other disorders, including pregnancy, if the metformin was able to restore your fertility, which is common.

Answered 3/13/2014

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Dr. Thomas Namey answered

Specializes in Rheumatology

No!: I have never seen metformin interrupt menses. However, the underlying metabolic syndrome, causing pcos may have gotten worse. Also, a low thyroid which you had causes excessive periods and bleeding. Correcting this may have given the impression that your menses were normal. Finally, if you are over treated with thyroid-you will be amennorheac.

Answered 12/10/2013

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