A member asked:

Daughter had hsp couple yrs ago and now has joint pain agsin no rash but pos ana and moderately high esr. is this connected? if not what else can be

4 doctors weighed in across 3 answers
Dr. Powlin Manuel answered

Specializes in Allergy and Immunology

May be connected!: Good morning, i can understand the reason for the worry about the positive ANA and high ESR following hsp, which represents an immune-mediated vasculitis, which is an inflammation triggered by an antigen such as a virus infection. The presence of ANA and high ESR shows continued hyperactivity of immune system. As an immunologist, i recommend a follow-up by a rheumatologist to keep an eye on ana.

Answered 6/10/2014

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Dr. Thomas Namey answered

Specializes in Rheumatology

Rheumatology!: See a rheumatologist. A doctor in this speciality is most likely to figure it out. An exam with your history and lab tests will be needed.

Answered 3/14/2013

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No: Positive ANA may suggest rather a different type of vasculitis. She should see a pediatric rheumatologist for further evaluation.

Answered 6/10/2014

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